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1

Identification of novel small molecules that elevate Klotho expression

King, Gwendalyn D., Chen, CiDi, Huang, Mickey M., Zeldich, Ella, Brazee, Patricia L., Schuman, Eli R., Robin, Maxime, Cuny, Gregory D., Glicksman, Marcie A., Abraham, Carmela R.

Journal:

Biochemical Journal

Year:

2012

Language:

english

File:

PDF, 582 KB

english, 2012

2

Intracranial glioblastoma models in preclinical neuro-oncology: neuropathological characterization and tumor progression

Marianela Candolfi, James F. Curtin, W. Stephen Nichols, AKM. G. Muhammad, Gwendalyn D. King, G. Elizabeth Pluhar, Elizabeth A. McNiel, John R. Ohlfest, Andrew B. Freese, Peter F. Moore, Jonathan Lern

Journal:

Journal of Neuro-Oncology

Year:

2007

Language:

english

File:

PDF, 1.76 MB

english, 2007

3

FGF-23 Deficiency Impairs Hippocampal-Dependent Cognitive Function

Laszczyk, Ann M., Nettles, Dailey, Pollock, Tate A., Fox, Stephanie, Garcia, Melissa L., Wang, Jing, Quarles, L. Darryl, King, Gwendalyn D.

Journal:

Year:

2019

Language:

english

File:

PDF, 1.80 MB

english, 2019

4

O1-03-07: Klotho, aging and Alzheimer's

Carmela R. Abraham, Sonia Podvin, Gwendalyn King, Ann McKee, Isabel Carreras, Alpaslan Dedeoglu, Ci-Di Chen

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 70 KB

english, 2008

5

Counter-regulatory paracrine actions of FGF-23 and 1,25(OH) 2 D in macrophages

Han, Xiaobin, Li, Linqiang, Yang, Jiancheng, King, Gwendalyn, Xiao, Zhousheng, Quarles, Leigh Darryl, Ellmeier, Wilfried

Journal:

Year:

2016

Language:

english

File:

PDF, 839 KB

english, 2016

6

424. Myd88/TLR Signaling Is Required for Immunotherapy-Mediated Glioblastoma Regression

Curtin, James F., King, Gwendalyn D., Candolfi, Marianela, Liu, Chunyan, Michelsen, Kathrin S., Arditi, Moshe, Fakhouri, Tamer M., Comin-Anduix, Begonya, Ribas, Antoni, Lowenstein, Pedro R., Castro, M

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 100 KB

english, 2006

7

Flt3L in Combination With HSV1-TK-mediated Gene Therapy Reverses Brain Tumor–induced Behavioral Deficits

King, Gwendalyn D, Kroeger, Kurt M, Bresee, Catherine J, Candolfi, Marianela, Liu, Chunyan, Manalo, Charlene M, Muhammad, AKM Ghulam, Pechnick, Robert N, Lowenstein, Pedro R, Castro, Maria G

Journal:

Molecular Therapy

Year:

2008

Language:

english

File:

PDF, 531 KB

english, 2008

8

621. Immunological Memory in a Syngeneic Model of Recurrent and Multifocal Glioblastoma

King, Gwendalyn D., Curtin, James F., Liu, Chunyan, Bresee, Catherine, Honig, Sarah B., Zirger, Jeffery M., VanRooijen, Nico, Ribas, Antoni, Pechnick, Robert, Lowenstein, Pedro R., Castro, Maria G.

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 83 KB

english, 2006

9

One-year Expression From High-capacity Adenoviral Vectors in the Brains of Animals With Pre-existing Anti-adenoviral Immunity: Clinical Implications

Barcia, Carlos, Jimenez-Dalmaroni, Maximiliano, Kroeger, Kurt M, Puntel, Mariana, Rapaport, Alison J, Larocque, Daniel, King, Gwendalyn D, Johnson, Stephen A, Liu, Chunyan, Xiong, Weidong, Candolfi, M

Journal:

Molecular Therapy

Year:

2007

Language:

english

File:

PDF, 619 KB

english, 2007

10

Plasmacytoid Dendritic Cells in the Tumor Microenvironment: Immune Targets for Glioma Therapeutics

Candolfi, Marianela, King, Gwendalyn D., Yagiz, Kader, Curtin, James F., Mineharu, Yohei, Muhammad, AKM Ghulam, Foulad, David, Kroeger, Kurt M., Barnett, Nick, Josien, Regis, Lowenstein, Pedro R., Cas

Journal:

Year:

2012

Language:

english

File:

PDF, 4.68 MB

english, 2012

11

Promoter methylation and age-related downregulation of Klotho in rhesus monkey

Gwendalyn D. King, Douglas L. Rosene, Carmela R. Abraham

Journal:

Year:

2012

Language:

english

File:

PDF, 1.09 MB

english, 2012

12

Cardiovascular Effects of Renal Distal Tubule Deletion of the FGF Receptor 1 Gene

Han, Xiaobin, Ross, Jed, Kolumam, Ganesh, Pi, Min, Sonoda, Junichiro, King, Gwendalyn, Quarles, L. Darryl

Journal:

Journal of the American Society of Nephrology

Year:

2017

Language:

english

File:

PDF, 2.25 MB

english, 2017

13

A chromatin modulator sustains self-renewal and enables differentiation of postnatal neural stem and progenitor cells

Shah, Kushani, King, Gwendalyn D, Jiang, Hao

Journal:

Journal of Molecular Cell Biology

Year:

2019

Language:

english

File:

PDF, 1.52 MB

english, 2019

14

P4-186: Modulating Klotho expression to protect against age-induced neurodegeneration

King, Gwendalyn D., Chen, Ci-Di, Podvin, Sonia, Abraham, Carmela R.

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 66 KB

english, 2008

15

Role of Fibroblast Growth Factor 23 and Klotho Crosstalk in Idiopathic Pulmonary Fibrosis

Barnes, Jarrod W, Duncan, Dawn, Helton, Scott, Hutcheson, Samuel, Kurundkar, Deepali, Logsdon, Naomi J, Locy, Morgan L, Garth, Jaleesa, Denson, Rebecca, Farver, Carol, Vo, Hai T, King, Gwendalyn, Kent

Journal:

American journal of physiology. Lung cellular and molecular physiology

Year:

2019

Language:

english

File:

PDF, 10.02 MB

english, 2019

16

The Effects of the Anti-aging Protein Klotho on Mucociliary Clearance

Garth, Jaleesa, Easter, Molly, Skylar Harris, Elex, Sailland, Juliette, Kuenzi, Lisa, Chung, Samuel, Dennis, John S., Baumlin, Nathalie, Adewale, Adegboyega T., Rowe, Steven M., King, Gwendalyn, Faul,

Journal:

Frontiers in Medicine

Year:

2020

File:

PDF, 6.47 MB

2020

17

Gene Therapy and Targeted Toxins for Glioma

King, Gwendalyn, Curtin, James, Candolfi, Marianela, Kroeger, Kurt, Lowenstein, Pedro, Castro, Maria

Journal:

Current Gene Therapy

Year:

2005

Language:

english

File:

PDF, 314 KB

english, 2005

18

Combining Cytotoxic and Immune-Mediated Gene Therapy to Treat Brain Tumors

Curtin, James, King, Gwendalyn, Candolfi, Marianela, Greeno, Remy, Kroeger, Kurt, Lowenstein, Pedro, Castro, Maria

Journal:

Current Topics in Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 474 KB

english, 2005

19

The Age-Regulating Protein Klotho Is Vital to Sustain Retinal Function

Reish, Nicholas J., Maltare, Astha, McKeown, Alex S., Laszczyk, Ann M., Kraft, Timothy W., Gross, Alecia K., King, Gwendalyn D.

Journal:

Investigative Opthalmology & Visual Science

Year:

2013

Language:

english

File:

PDF, 2.16 MB

english, 2013

20

Adaptor protein interactions: modulators of amyloid precursor protein metabolism and Alzheimer's disease risk?

Gwendalyn D. King, R. Scott Turner

Journal:

Experimental Neurology

Year:

2004

Language:

english

File:

PDF, 502 KB

english, 2004

21

Development and Characterization of Monoclonal Antibodies to Detect Klotho

Maltare, Astha, Nietz, Angela K., Laszczyk, Ann M., Dunn, Taylor S., Ballestas, Mary E., Accavitti-Loper, Mary Ann, King, Gwendalyn D.

Journal:

Monoclonal Antibodies in Immunodiagnosis and Immunotherapy

Year:

2014

Language:

english

File:

PDF, 612 KB

english, 2014

22

Klotho regulates CA1 hippocampal synaptic plasticity

Li, Qin, Vo, Hai T., Wang, Jing, Fox-Quick, Stephanie, Dobrunz, Lynn E., King, Gwendalyn D.

Journal:

Year:

2017

Language:

english

File:

PDF, 5.87 MB

english, 2017

23

Klotho, the Key to Healthy Brain Aging?

Vo, Hai T., Laszczyk, Ann M., King, Gwendalyn D., Luikart, Bryan W.

Journal:

Brain Plasticity

Year:

2018

Language:

english

File:

PDF, 512 KB

english, 2018

24

Development of Klotho enhancers as novel therapeutics for Alzheimer's disease

Abraham, Carmela R., Chen, Ci-Di, King, Gwendalyn D.

Journal:

Alzheimer's & Dementia

Year:

2010

Language:

english

File:

PDF, 43 KB

english, 2010

25

Expression of klotho mRNA and protein in rat brain parenchyma from early postnatal development into adulthood

Clinton, Sarah M., Glover, Matthew E., Maltare, Astha, Laszczyk, Ann M., Mehi, Stephen J., Simmons, Rebecca K., King, Gwendalyn D.

Journal:

Year:

2013

Language:

english

File:

PDF, 4.09 MB

english, 2013

26

Differential Regulatory Role of Soluble Klothos on Cardiac Fibrogenesis in Hypertension

Liu, Xue, Chen, Yuanjian, McCoy, Cody W., Zhao, Tieqiang, Quarles, Darryl L., Pi, Min, Bhattacharya, Syamal K., King, Gwendalyn, Sun, Yao

Journal:

American Journal of Hypertension

Year:

2016

Language:

english

File:

PDF, 945 KB

english, 2016

27

X11α impairs γ- but not β-cleavage of amyloid precursor protein

Gwendalyn D. King, Kay Cherian, R. Scott Turner

Journal:

Journal of Neurochemistry

Year:

2004

Language:

english

File:

PDF, 486 KB

english, 2004

28

MicroRNA-339 and microRNA-556 regulate Klotho expression in vitro

Stephen J. Mehi, Astha Maltare, Carmela R. Abraham, Gwendalyn D. King

Journal:

Year:

2014

Language:

english

File:

PDF, 659 KB

english, 2014

29

Ubiquitin-specific protease 14 regulates c-Jun N-terminal kinase signaling at the neuromuscular junction

Vaden, Jada H, Bhattacharyya, Bula J, Chen, Ping-Chung, Watson, Jennifer A, Marshall, Andrea G, Phillips, Scott E, Wilson, Julie A, King, Gwendalyn D, Miller, Richard J, Wilson, Scott M

Journal:

Molecular Neurodegeneration

Year:

2015

Language:

english

File:

PDF, 3.29 MB

english, 2015

30

Role of Fibroblast Growth Factor 23 and Klotho Crosstalk in Idiopathic Pulmonary Fibrosis

Barnes, Jarrod W, Duncan, Dawn, Helton, Scott, Hutcheson, Samuel, Kurundkar, Deepali, Logsdon, Naomi J, Locy, Morgan L, Garth, Jaleesa, Denson, Rebecca, Farver, Carol, Vo, Hai T, King, Gwendalyn, Kent

Journal:

American journal of physiology. Lung cellular and molecular physiology

Year:

2019

File:

PDF, 10.02 MB

2019

31

Combined Flt3L/TK Gene Therapy Induces Immunological Surveillance Which Mediates an Immune Response Against a Surrogate Brain Tumor Neoantigen

King, Gwendalyn D, Muhammad, AKM Ghulam, Larocque, Daniel, Kelson, Kyle R, Xiong, Weidong, Liu, Chunyan, Sanderson, Nicholas SR, Kroeger, Kurt M, Castro, Maria G, Lowenstein, Pedro R

Journal:

Molecular Therapy

Year:

2011

Language:

english

File:

PDF, 616 KB

english, 2011

32

Klotho deficiency affects the spine morphology and network synchronization of neurons

Vo, Hai T., Phillips, Mary L., Herskowitz, Jeremy H., King, Gwendalyn D.

Journal:

Molecular and Cellular Neuroscience

Year:

2019

Language:

english

File:

PDF, 4.81 MB

english, 2019

33

Klotho regulates postnatal neurogenesis and protects against age-related spatial memory loss

Laszczyk, Ann M., Fox-Quick, Stephanie, Vo, Hai T., Nettles, Dailey, Pugh, Phyllis C., Overstreet-Wadiche, Linda, King, Gwendalyn D.

Journal:

Neurobiology of Aging

Year:

2017

Language:

english

File:

PDF, 2.79 MB

english, 2017

34

999. Mature Effector Immunological Synapses Forming SMAC Mediate Clearance of Virally Infected Astrocytes from the Brain In Vivo

Barcia, Carlos, Thomas, Clare, Curtin, James F., King, Gwendalyn D., Wawrowsky, Kolja, Candolfi, Marianela, Xiong, Wei-Dong, Chunyan, Liu, Kroeger, Kurt, Boyer, Olivier, Kupiec-Weglinski, Jerzy, Klatz

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 82 KB

english, 2006

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